Best Mattresses for Allergies in 2025: How To Choose a Hypoallergenic Mattress

What is the best mattress for allergies? 

With polyurethane foam construction and low VOCs, the Purple Essentials collection offers mattresses made with hypoallergenic materials to help you get a good night’s sleep and reduce allergy symptoms.

It may not be the first thing you think of when buying a mattress, but allergies can be a meaningful sleep disruptor. Bedroom allergens like dust mites, pet dander, pollen, and even indoor mold can get trapped in your bed. 

When this happens, symptoms like itchy eyes, nasal congestion, and even rashes or swelling can make it difficult to fall or stay asleep.¹  If this sounds like you, switching to a mattress made with hypoallergenic materials may help reduce your exposure to common irritants.

The best mattress for allergies likely features hypoallergenic components like polyurethane foam or natural latex, along with allergen-resistant coverings like cotton, to keep irritants at bay. A quality mattress designed to reduce allergens may help minimize your allergy symptoms by minimizing exposure to VOCs and off-gassing.

Read along to learn more about the best mattresses for different types of allergies.

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What Is the Best Bed for Allergies?

A bed designed for allergies is specifically crafted with your allergy or asthma symptoms in mind. These easy-to-clean beds utilize materials like polyurethane foam or natural latex that resist allergens and emit low levels of volatile organic compounds (VOCs).

A mattress made with hypoallergenic materials can help by:

• Reducing your exposure to allergens
• Relieving sneezing, skin irritation, scratchy throat, and other symptoms
• Improving your sleep quality
• Providing a more hygienic mattress for healthy sleep
• Improving your overall indoor air quality

Best Mattress for Allergy-Sensitive Sleepers: The Purple Mattress® 

Alternative for: Nolah Natural or Avocado Green Mattress

The Purple Mattress®’s GelFlex Grid® is made with a Hyper-Elastic Polymer, while the comfort and base layers are made with polyurethane foam. These materials help prevent dust mites, pollen, and other allergens from accumulating inside your mattress. The GelFlex Grid’s breathability and airflow can help you sleep cooler while making it even harder for allergens to take hold.

Our GelFlex Grid®, which is designed to instantly adapt to your preferred sleep position, cradles your pressure points and provides support for better posture and more comfortable sleep. Pairing the mattress with a compatible adjustable base can help you find your optimal sleep position while also promoting better airflow in your room. 

• Key features: 9.25” thickness, 2” GelFlex Grid®, Comfort Foam, Edge Support Foam, Base Support Foam, Softflex Cover
• Sizes: Twin, Twin XL, Full, Queen, King, Cal King, Split King
• Price: $999-$2,198

“The mattress really is unbelievable. I have allergies so I appreciate the science and all the amazing materials that make up Purple products. I love sleeping on this mattress, it is everything I hoped it would be.” — Barbara T., Purple Mattress® review 

Best Latex-Free Mattress: PurpleFlex™ Mattress

Alternative for: Layla Memory Foam Mattress

Latex mattresses are a popular pick for those seeking mattresses with hypoallergenic properties — but if you’re allergic to latex, they could make your symptoms worse. The PurpleFlex™ Mattress doesn’t contain latex, making it one of the best options for those with latex allergies.

With our Hyper-Elastic Polymer GelFlex Grid® and polyurethane foam for the base layer, you won’t have to worry about your mattress materials causing rashes or itching.

This firm mattress provides significant airflow thanks to the 2-inch GelFlex Grid®, which not only helps you sleep up to two times cooler than other comparable mattresses, but also makes it harder for allergens to accumulate within the mattress. Stable base support conforms to your contours to relieve pressure on the hips and shoulders.

• Key features: 8” thickness, 2” GelFlex Grid®, Edge Support Foam, Base Support Foam, Softflex Cover
• Sizes: Twin, Twin XL, Full, Queen, King, Split King
• Price: $699-$1,698

“Mattress is really awesome, plus because of the material it is made out of, dust mites can't thrive on it!” — Breanna M., PurpleFlex™ review 

Non-Toxic Mattress for Better Sleep: Restore® Hybrid Mattress

Alternative for: DreamCloud Premier Hybrid or Saatva Latex Hybrid Mattress

The Restore® Hybrid Mattress keeps you cool with non-toxic materials for a superior night’s sleep. The GelFlex Grid® dissipates heat, allowing for cooler sleep so you can fall asleep faster and sleep deeper. Responsive Edge-to-Edge Coils promote better airflow while also providing the support your body needs, even as you shift your position. With CertiPUR‑US® certified foam and Clean Air GOLD certification, Purple mattresses like the Restore® Hybrid are certified to have low VOCs for better indoor air quality.

Debating whether you need a mattress protector? Thanks to its antimicrobial finish, the Softflex Cover on the Restore® Hybrid Mattress helps inhibit the growth of bacteria and other microorganisms. This way, you get the comfort and cooling you need, even as you get extra protection against dust mites and other allergens — without the need for an additional mattress protector.

• Key features: 11.5” thickness, 2” GelFlex Grid®, Edge-to-Edge Coils, Edge Support System, Antimicrobial Finish, Comfort Layer
• Sizes: Twin XL, Full, Queen, King, Cal King, Split King
• Price: $1,999-$3,998

“We love our new Purple mattress! It is so comfortable! Both my husband and I are sleeping much better, when one of us moves, the other person can barely feel it which promotes more sleep for the both of us! ” — Michelle G., Restore® Hybrid review

Best Bedroom Accessories for Allergies

Selecting a mattress made with hypoallergenic materials is a good start, but it’s just one piece of the puzzle. As Tyler Wright, Purple’s Senior Product Manager of Mattresses, advises, “In addition to finding a mattress made with hypoallergenic materials, you should also find bedding such as sheets, mattress protectors, and pillowcases that may help create barriers against allergens and dust mites.”

If you struggle with bedroom allergies, these extra accessories can also make a difference:

• Mattress protector: A mattress protector provides an important barrier that can help keep allergens from accumulating inside a mattress. In addition to providing a barrier against allergens, spills, and more, these mattress protectors are usually washer and dryer safe for easy care. The Purple Waterproof Mattress Protector is our pick for the best hypoallergenic mattress protector.
• Pillows with hypoallergenic materials: Pillows like the Purple Harmony™ Pillow are made from materials less likely to attract and trap common allergens. The Purple Harmony™ Pillow is available in configurations for stomach, back, and side sleepers.
• Sheets: Sheets for allergies are tightly woven with a high thread count and made with natural materials like bamboo and 100% natural cotton. This can be especially helpful in reducing exposure to dust mites, particularly with regular washing. The Purple SoftStretch® Sheet Set with pillowcases is made from bamboo viscose for temperature regulation so you don’t sleep too hot or too cold.
• Bed frame or base: Wright notes, “An adjustable base can help improve airflow around your mattress and reduce moisture buildup, which can lead to mold.” With adjustable head and leg heights, the Purple Adjustable Base may help you find a comfortable sleep position while also potentially reducing allergy symptoms.
• Air purifier: Air purifiers are designed to filter dust, pollen, and other allergens from the air. Air purifiers are available in many different sizes to filter the entire home or just your bedroom.

What To Look for in a Mattress for Allergies

When trying to find the best mattress for allergies and asthma, there are certain traits you should look for. By focusing on key features like the mattress material and certifications, as well as its base and bed frame compatibility, size capacity, and additional functionality, you can get a mattress that may help reduce allergy symptoms and support healthy sleep.

Mattress Material

With so many different types of mattresses available, an important thing to consider in a mattress is the type of material used. Some materials are more likely to attract and trap dead skin cells, dust mites, and other allergens. On the other hand, certain materials may keep allergens from taking hold in your mattress.

These materials are the best options for reducing allergies:

• GelFlex Grid®: Purple mattresses incorporate polyurethane foam, a material with hypoallergenic properties that is also low in VOCs and has no harmful CFCs. The cutting-edge foam structure of the GelFlex Grid® also facilitates airflow in a way that makes it harder for allergens to take hold within the mattress.
• Memory foam: Memory foam uses a dense, closed-cell structure that makes it hard for allergens to accumulate and grow. As a synthetic material, it is naturally resistant to allergens, but some memory foam mattresses can off-gas chemicals and cause irritation.
• Natural latex: Natural latex is made from the sap of the rubber tree, which gives it natural resistance to allergens like dust mites, mold, and pollen. While it doesn’t usually have any off-gassing, a natural latex mattress isn’t a good choice if you have latex allergies.

Certifications

The mattress industry has many different certifications to ensure mattresses meet safety standards, possess certain properties, or meet other important requirements. When shopping for a mattress for allergies, these are some certifications to look for:

• CertiPUR-US: CertiPUR-US certification requires that mattresses are made without formaldehyde, zone depleters, phthalates, heavy metals, or harmful chemicals — all of which can aggravate asthma and allergy symptoms. All Purple mattresses are CertiPUR-US certified, with low VOCs and safe materials.
• Intertek Clean Air: The Intertek Clean Air certification tests a wide range of products for VOC compliance. Purple’s mattresses are Clean Air GOLD certified, meaning they contribute to improved indoor air quality.
• GREENGUARD: GREENGUARD certification sets emission limits for hypoallergenic mattresses and other furniture items to ensure they meet chemical emissions requirements.
• OEKO-TEX: OEKO-TEX tests mattresses and other textile products for harmful chemicals.

Base and Bed Frame Compatibility

Choosing the best bed frame for allergies is another important part of buying a mattress. For example, an adjustable base can be used to lift the head or feet to improve airflow in the room, and it also makes it easier to clean behind and beneath the bed to reduce dust or mildew buildup.

If you’re considering an adjustable base or another specialty bed frame, check the mattress’s specifications to ensure it’s compatible.

Size and Weight Capacity

Choosing the right size bed also matters. A bed that has enough space for you and/or others to sleep comfortably is important. For allergy purposes, make sure the bed fits your room properly by not blocking vents and by having enough space between it and the walls or other furniture. This helps promote better airflow throughout the room.

Bedding Material

Your mattress is only part of the story. The best sheets for allergies are breathable, with a high thread count and hypoallergenic materials. This type of construction makes it harder for dust mites and other allergens to get lodged in your sheets. Bamboo and organic cotton are usually considered the best sheet materials if you suffer from asthma or allergies. 

Trial Period and Warranty

Even if a mattress seems like a good fit for allergies, it never hurts to test it out. Make sure your new mattress comes with a generous trial period and warranty. This way, you can switch to a different option if the first mattress you try doesn’t help your symptoms or feels uncomfortable. Purple mattresses come with a 100-night sleep trial and a best-in-class warranty.

Are Mattresses Made With Hypoallergenic Materials Worth It?

Getting a mattress made with hypoallergenic materials can help reduce exposure to allergens and improve comfort for some people with allergies. Purple mattresses contain materials with hypoallergenic properties that can make it more difficult for dust mites and other allergens to build up. Reducing allergy triggers at night can reduce nighttime discomfort and support healthy sleep.

Mattresses with hypoallergenic materials aren’t the be-all and end-all for allergy relief. As Wright notes, “A hypoallergenic mattress is helpful, but regular maintenance like washing bedding weekly/regularly, spot-cleaning the mattress when needed, and using dust-mite-proof covers is also important.”

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