How To Choose the Best Mattress for Adjustable Beds in 2025

Key Takeaways

• An adjustable base can elevate your head and legs during sleep. This can make it easier to relax, while also improving breathing and blood circulation during sleep. 
• The best mattress for an adjustable bed should be flexible and durable, so you can still get the right level of comfort and sleep quality when using an adjustable base.

An adjustable base can make a big difference for your sleep quality. But just as important as the base is the mattress you pick to go along with it. Different types of mattresses work better for different types of bed frames, and the same is true when trying to find the best mattress for adjustable bed frames. 

Not all mattresses are compatible with an adjustable base. You’ll need a flexible, durable mattress so you can get the quality sleep you need, while also ensuring that your mattress stands the test of time.

Read on to learn more about which mattresses work best for an adjustable bed base.

Purple Adjustable Base

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What Type of Mattress is Best for an Adjustable Bed?

Wondering if you need a special mattress for adjustable beds? Don’t worry. You don’t necessarily need a special mattress — you just need a compatible one.

Mattress compatibility with an adjustable base depends on its materials, articulation, durability, and back support. For example, mattresses that are less than 13 inches thick and made with flexible materials like latex or memory foam will work better than thicker innerspring mattresses.

Here are some things to consider when looking for the best mattress for an adjustable bed:

• Material: Latex, memory foam, and hybrid mattresses are usually flexible enough to bend when using an adjustable base.
• Articulation: This is a mattress’s ability to bend and flex, allowing parts to raise or lower to different heights. The more flexible the mattress, the easier it is to adjust to your preferred settings.
• Durability: Materials like hyper-elastic polymer, dense memory foam, and latex work best on adjustable bases. Choose a mattress with pocketed coils instead of innerspring coils; pocketed coils aren’t interconnected like innersprings, allowing for independent movement.

Based on the type of mattress you prefer, you may find different options better suited for an adjustable base.

Best Value Mattress for Adjustable Bed: PurpleFlex™ Mattress

Alternative to: Nectar Mattress

If you’re looking for affordable adjustable beds (including a twin mattress for adjustable bed frames), the PurpleFlex™ Mattress is a great value choice that pairs well with a simple adjustable base. With its firm feel and 2” GelFlex Grid® (or Gel Matrix™) that cradles your pressure points, this mattress doesn’t sacrifice comfort or quality. 

The PurpleFlex™ Mattress ensures a great night’s sleep with its durable Base Support Foam that promotes proper spinal alignment and reduces motion transfer. Whether you’re looking for the best twin XL mattress for adjustable bed base or a mattress for adjustable bed queen, this mattress gives the right balance of value and performance.

• Key Features: 8” thickness, 2” GelFlex Grid®, Edge Support Foam, Base Support Foam, SoftFlex Cover
• Materials: Non-toxic, hypoallergenic, Certified Clean Air GOLD
• Sizes: Twin, Twin XL, Full, Queen, King, Split King
• Price: $699-$1,698

Reviewers love how the PurpleFlex™ relieves back pain and insomnia, making it easier to get a full night’s sleep.

“Mattress works great for back/neck pain. It's not too soft or too firm and doesn't sink in. It works really good with an adjustable frame as well.” — Kyle S, PurpleFlex™ review

If value is a priority when trying to find the best mattress for adjustable bed frames, be sure to check out the PurpleFlex™.

Best Mattress for Couples With an Adjustable Bed: The Purple Mattress®

Alternative to: Tempur-Pedic TEMPUR-Cloud

For superior motion isolation and pressure relief, the original Purple Mattress® is a perfect choice for couples. Paired with an adjustable base, this innovative mattress can provide custom comfort that instantly adapts to your body no matter what position you’re in.

At just over 9” thick, the Purple Mattress® is a great choice for an adjustable bed; the flexible GelFlex Grid® can easily bend with your base without compromising its integrity or your comfort.

• Key Features: Adaptive, breathable GelFlex® Grid keeps you temperature-neutral with plenty of pressure relief
• Materials: GelFlex® Grid, Comfort Foam, Base Support Foam
• Sizes: Twin, Twin XL, Full, Queen, King, Cal King, Split King
• Price: $999-$2,198

Reviewers love how the Purple Mattress® offers soothing pressure relief and support for a restful night’s sleep.

“We've had this mattress for 6 months now and it's been so great! I'm currently 32 weeks pregnant and I have not had to use any sort of support pillow while sleeping. I have slept the best during this pregnancy (baby #4) all because of my Purple mattress!” — Holly, Purple Mattress® review

Experience the adaptive comfort of the Purple Mattress® for yourself.

Best Cooling Mattress for Adjustable Bed: RestorePremier® Hybrid

Alternative to: Bear Elite Hybrid

Hot sleepers in need of night time relief should check out the RestorePremier® Hybrid, our most cooling bed. All Purple Hybrids™ provide ample support and pressure relief with enough articulation to work with an adjustable base, but the RestorePremier® tops the list. Named the Best Cooling Mattress for an Adjustable Bed by Good Housekeeping, the breathability of this mattress will help even the hottest sleepers feel cool.¹

The flexibility of the GelFlex Grid® makes the RestorePremier® Hybrid perfect for an adjustable base, including a zero gravity position. Ultra Comfort Foam and Coolflex Coils offer targeted cradling of your pressure points, while still helping you keep cool.

• Key Features: 13” thickness, 3” GelFlex Grid®, Ultra Comfort Foam, CoolFlex Coils, Advanced Edge Support System, Antimicrobial Finish, Moisture-Wicking Cover
• Materials: Non-toxic, hypoallergenic, Certified Clean Air GOLD
• Sizes: Twin XL, Queen, King, Cal King, Split King
• Price: $3,249-$6,498

Reviewers love how the RestorePremier® Hybrid provides incredible cooling along with comfort and pressure relief.

“My wife and I are truly impressed with this mattress. It truly has a cooling feeling, but it is, more importantly, supportive where necessary, and soft elsewhere.” — Kevin H, RestorePremier® Hybrid review

With its impressive back support and incredible cooling capabilities, the RestorePremier® Hybrid could be your ticket to great sleep on an adjustable mattress.

Best Pressure Relief Mattress for Adjustable Bed: RestorePlus® Hybrid

Alternative to: DreamCloud Premier Hybrid

If pressure point pain is making it hard for you to sleep, the RestorePlus® Hybrid is the pressure relief mattress you’re looking for. By contouring to and cushioning pressure points like your hips and shoulders, this mattress offers targeted support for back and side sleepers alike.

The RestorePlus® Hybrid accomplishes this by pairing a 3” GelFlex Grid® with 3-Zone Edge to Edge coils. This allows the mattress to adapt to any sleep position by specifically targeting common problem areas like your shoulders, hips, and back. This maximizes the comfort you get when using an adjustable base for high-quality, uninterrupted sleep.

• Key Features: 13” thickness, 3” GelFlex Grid®, 3 Zone Edge-to-Edge Coils, Advanced Edge Support System, Ultra Comfort Layer, Antimicrobial Finish, Moisture-Wicking Cover
• Materials:  Non-toxic, hypoallergenic, Certified Clean Air GOLD
• Sizes: Twin XL, Full, Queen, King, Cal King, Split King
• Price: $2,549-$5,098

The pressure relief that the RestorePlus® Hybrid offers for both side sleepers and back sleepers makes it one of our most popular models.

“The best feature of this mattress is its ability to provide substantial pressure relief. I suffer from shoulder pain and lower back pain. This has been the best solution!” — Carmen J, RestorePlus® review

If joint pain has been keeping you up at night, the RestorePlus® Hybrid could be the perfect match for your adjustable bed.

Best Mattress for Adjustable Bed Base With Lumbar Support: Restore® Hybrid

Alternative to: Nolah Evolution

Body pain can make it impossible to get a good night’s sleep, especially for back sleepers. Enter the best hybrid mattress for an adjustable base with lumbar support: the Restore® Hybrid. The Restore® Hybrid is already one of the best mattresses for back pain, and pairing it with an adjustable base can enhance your nighttime comfort even more.

The Restore® Hybrid balances comfort and value by pairing a 2” GelFlex Grid® with edge-to-edge coils for responsive support. The comfort foam layer provides a medium feel and an adaptive support system for back pain relief. By using the Restore® Hybrid with an adjustable base, you can get even more lumbar support for blissful sleep.

• Key Features: 11.5” thickness, 2” GelFlex Grid®, Edge-to-Edge Coils, Edge Support System, Comfort Layer, Antimicrobial Finish
• Materials: Non-toxic, hypoallergenic, Certified Clean Air GOLD
• Sizes: Twin XL, Full, Queen, King, Cal King, Split King
• Price: $1,999-$3,998

The Restore® Hybrid’s lumbar support makes it a popular choice for reviewers who use an adjustable base for their bed.

“The comfort for me is second to none and that, coupled with an adjustable base made my ideal bed.” — Robert C, Restore® Hybrid review

Make back pain a thing of the past with the Restore® Hybrid.

Best Adjustable Bed and Mattress Combo: Rejuvenate™ + Purple Premium Plus Smart Base

Alternative to: Sleep Number 360 p6 Smart Bed

If you’re looking for the best mattress with adjustable base options, you can’t go wrong with the Rejuvenate® – the Men’s Health Best Pressure Relief Mattress of 2025². At 15.5” thick, this luxury mattress is thicker than what is typically recommended for an adjustable base. However, the flexible construction still allows it to be used with adjustable bases like the Purple Premium Plus Smart Base.

The Purple Premium Plus Smart Base is the perfect adjustable bed frame for this luxe mattress, with features like adjustable lumbar support, pillow tilt, and other smart features. With DreamLayer technology, Active Response Foam, and Dynamic Grid Support, you’ll enjoy incredible comfort and support in any sleep position.

• Key Features: 15.5” thickness, Luxury Cover, DreamLayer Technology, 2” GelFlex Grid®, Active Response Foam, Dynamic Grid Support
• Materials: Non-toxic, hypoallergenic, Certified Clean Air GOLD
• Sizes: Twin XL, Full, Queen, King, Cal King, Split King
• Price: $4,499-$8,998

The Rejuvenate® provides the maximum level of comfort, temperature balance, and pressure relief.

“During our month-long test, this sumptuous hybrid delivered instant comfort and ergonomic support…We also found that it offers superb pressure relief around the back, shoulders and hips.” – Tom’s Guide Rejuvenate® review³

Enjoy a luxurious sleep experience without giving up the ability to use an adjustable base.

How To Choose a Mattress for an Adjustable Base

The good news about trying to find the best adjustable bed and mattress combo is that there are plenty of options to choose from! But with so many mattresses out there, that search can start to feel a little overwhelming.

Fortunately, there are some basic steps you can follow to find the best mattress for adjustable bed frames and your specific needs.

1. Narrow Down Mattress Types

Each type of mattress has its own durability and articulation (or flexibility). Brooke Reynolds, Purple’s Senior Product Manager of Bases, says, “Flexibility and durability of the mattress is the most important factor when selecting a mattress to pair with an adjustable base. The mattress needs to be able to bend while maintaining its structural strength.”

Start by narrowing down your search to mattresses that use flexible materials. Some examples of good materials for adjustable beds include:

• Innerspring
• Memory foam
• Latex 
• Hybrid

2. Measure Mattress Thickness

Mattress thickness will also affect whether the mattress is a good fit for an adjustable bed. Basically, the thicker the mattress, the less flexible it will be. A mattress that is too thick will have trouble bending as much as you need.

Most modern mattresses are between 9” and 12” thick, which works well with adjustable beds. Mattresses that are more than 13” thick won’t be as flexible unless made specially to pair with an adjustable base.

3. Assess Compatibility

Even if a mattress’s materials and thickness make it seem compatible with adjustable bed frames, you should still double check. Most manufacturers will tell you if their mattresses are compatible with an adjustable base. In some cases, the warranty might also have restrictions on using an adjustable bed. You don’t want to accidentally void the warranty!

As Brooke Reynolds explains, “Purple mattresses are all designed to be paired with adjustable bases. The base material of the mattresses is either independent coils or support foam, both of which can bend and are highly durable.”

4. Consider Your Sleep Position

Your sleep position will also affect your mattress choice and whether an adjustable base is right for you. For example, back sleepers often benefit by raising their head during sleep to help relieve sleep apnea and acid reflux.⁴ An adjustable base can also reduce lower back pain.

No matter what your preferred sleep position is, make sure your mattress provides proper support for your pressure points so you can enjoy a comfortable night’s sleep.

5. Review the Trial Period and Warranty

When testing out a new mattress with an adjustable base, a lengthy sleep trial can be a big help. At Purple, we offer a 100 night sleep trial on mattresses, giving you plenty of time to test your mattress and see if it’s right for you. We also offer a 10-year warranty to replace your mattress if there’s something wrong with it.

A good trial period and warranty can give you peace of mind as you test your new mattress to see if it’s a good fit for your adjustable bed.

Be aware that trials may vary between mattresses and bases. Your base may have a different trial length and restrictions than your mattress, even if you purchase them from the same manufacturer.

6. Research Delivery and Set-Up Services

Mattress delivery and set-up services can also make choosing a mattress easier. Some companies (like Purple) offer delivery and set-up – even for a king size mattress for adjustable bed frames – to ensure your mattress is correctly aligned on the adjustable base.

7. Consider Body Weight

Your body weight can also affect what type of mattress is right for you. Heavier individuals usually prefer a firmer mattress that provides more support. However, these firmer and thicker mattresses may have less articulation. Check mattress descriptions and reviews to see which body types they’re best for.

You’ll also need to look at the weight limits for the adjustable base. Each adjustable base has a weight limit for the mattress and its users. A mattress that is too heavy could damage the base.

8. Identify the Features You Want

Compatibility with an adjustable base isn’t the only feature you’ll want to consider! From pressure relief to temperature balancing, the right features will help you sleep better than ever.

Some features you might want to look for in an adjustable bed mattress include:

• Temperature balancing/cooling
• Edge support
• Motion isolation
• Antimicrobial finish
• Moisture wicking
• Pressure point support

9. Account for Your Budget

Finally, make sure to budget for both your mattress and its adjustable bed frame. Adjustable Mattresses and bases offer different features and benefits at different price points. Whether you’re looking for the best firm mattress for adjustable bed frames or a split king, you can choose from a wide range of mattresses depending on the type of base you have and the features you want.

10. Check for HSA/FSA Eligibility

Looking for more ways to make a smart investment in your sleep? If you have a Health Savings Account (HSA) or Flexible Spending Account (FSA), you may be able to use those pre-tax dollars toward the purchase of a Purple mattress — especially if your mattress supports medical needs like back pain or better spinal alignment.

We’ve teamed up with TrueMed to make the process easy. During checkout, you can verify your eligibility in just a few steps — no confusing paperwork or guesswork required. It’s a simple way to save more while prioritizing your health and comfort.

Want to learn more? Visit our HSA/FSA page to see if you qualify and explore eligible products.

What is the Best Adjustable Bed and Mattress?

An adjustable bed can make a huge difference for your sleep quality, especially when you focus on finding the best fit for your sleep needs. With the best mattress for adjustable bed frames (and the best adjustable bed frame to go with it), you can transform your nightly sleep with reduced aches and pains and better sleep quality.

Explore Purple’s wide range of adjustable mattresses so you can start enjoying better sleep. 

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